Medullary sponge kidney - the mysterious name of a simple disease

Medullary sponge kidney (renal spongiosis), (MSK) is a rare developmental anomaly of the unknown cause. It presumed, that people with genetic predisposition (<5% family occurrence) are prone to disease. The peak diagnosis between ages 20-50, usually by chance (due lack symptoms) during an abdominal X-ray, where so-called nephrocalcinosis (calcifications in kidney) can be observed. Another radiologic test, may suggest condition question ultrasound, cysts up 8 mm diameter medullary part and calcifications seen. Diagnosis also based on pre-existing stones urinary tract infections, or hematuria. Urography has highest sensitivity kidney. Symptoms, if already present, characterized low back pain, hematuria, recurrent proteinuria, sterile purulence. Ultimately, aforementioned pathologies lead failure. To date, no causal treatment been developed; only symptomatic lithiasis foci infections possible. purpose following paper was describe definition, epidemiology etiology MSK highlight randomness problem specific therapy for this renal disorder. Current publications guidelines from scientific societies around world were reviewed, using MeSH-compliant keywords.